ISSN 1849-9031 (Online)

ISSN 1849-8922    (Print)

The patient with severe sideropenic anemia and giant solitary ovarian tumor.
Ivka Djaković, Nenad Babić, Tanja Leniček, Dražan Butorac.


Ovarian tumors composed of granulosa cells represent 1-3% of all ovarian tumors. They are commonly estrogen secreting tumors. We present a case of a postmenopausal woman who presented with severe anemia, metrorrhagia, and a palpable tumor mass in her lower right abdomen. Subsequent diagnostic work-up confirmed a gigantic granulosa-cell tumor of the right ovary. This case highlights that the presence of metrorrhagia in a postmenopausal women with an ovarian tumor should always raise the suspicion of a granulosa-cell tumor. Gonadotropins, estradiol, and inhibin B should be measured to establish the diagnosis preoperatively. This could potentially help in treatment decision-making and long-term follow-up.